Investigators and Instructors must ensure the humane use of animals. They have ultimate responsibility to ensure that animals are adequately cared for in a humane fashion. It is the responsibility of the investigator to:

• Document the training and experience of the personnel involved;
• Design and perform procedures on the basis of relevance to human or animal health, advancement of knowledge, or the  good of society;
• Use the appropriate species, quality, and number of animals to obtain valid results;
• Avoid or minimize discomfort, distress, and pain in concert with sound science;
• Use appropriate sedation, analgesia, or anesthesia;
• Establish experimental end points;
• Provide appropriate animal husbandry and veterinary care directed and performed by qualified persons;
• Conduct experiments on animals only under the close supervision of qualified and experienced persons;
• Consider alternatives to procedures that may cause more than momentary of slight pain and distress;
• Avoid unnecessary duplication of experiments;
• Expected to consult with the attending veterinarian in planning animal uses involving more than minimal pain and distress;
• Provide appropriate peri-operative care to animals;
• Obtain IACUC approval prior to the initiation of animal work.

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STEP 1: PREPARE TO SUBMIT YOUR PROTOCOL APPLICATION
STEP 2:  ADMINISTRATIVE REVIEW
STEP 3: COMMITTEE REVIEW
STEP 4: APPROVAL OUTCOME
STEP 5: CHANGES TO A PROTOCOL
STEP 6: CLOSURE OF A PROTOCOL